Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10738160 | Free Radical Biology and Medicine | 2012 | 14 Pages |
Abstract
⺠Nitric oxide dose-dependently inhibits NADPH oxidase activity. ⺠Reduced Nox5 activity was not due to nitration, glutathiolation or phosphorylation. ⺠Nox5 was S-nitrosylated on at least 4 sites and SNO-Nox5 reduced by C694S mutation. ⺠Sensitivity to NO inhibition varied across Nox isoforms, Nox1â¥Nox3>Nox5>Nox2>Nox4.
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Authors
Jin Qian, Feng Chen, Yevgeniy Kovalenkov, Deepesh Pandey, M. Arthur Moseley, Matthew W. Foster, Stephen M. Black, Richard C. Venema, David W. Stepp, David J.R. Fulton,