Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10738166 | Free Radical Biology and Medicine | 2012 | 9 Pages |
Abstract
⺠Vancomycin chloride (VCM) causes apoptosis in LLC-PK1 cells by enhancing caspase activity. ⺠VCM induces depolarization of the mitochondrial membrane in LLC-PK1 cells. ⺠VCM-induced inactivation of mitochondrial complex I leads to superoxide production.
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Authors
Yohei Arimura, Takahisa Yano, Megumi Hirano, Yuya Sakamoto, Nobuaki Egashira, Ryozo Oishi,