| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10738183 | Free Radical Biology and Medicine | 2012 | 12 Pages |
Abstract
⺠Zinc is part of the antioxidant network protecting biological systems from oxidative stress. ⺠Protein thiol-bound zinc participates in redox sensing. ⺠Zinc regulates proteins directly or indirectly involved in redox homeostasis. ⺠Zinc can modulate redox signaling through multiple mechanisms. ⺠NO and oxidants release zinc bound to sulfur clusters.
Keywords
NMDARNMDAGCLN-methyl-d-aspartatePTPGPCRERKPKCGSHNrf2MORRetinoid X receptorJnkVDRRXRJun N-terminal kinaseKelch-like ECH-associated proteinBDNFkeap1G-protein-coupled receptorMAPKAntioxidantAktOxidative stressThiolsFree radicalsRedox signalingBrain-derived neurotrophic factorZincGlutamate–cysteine ligaseMetallothioneinNitric oxideRedox homeostasisProtein tyrosine phosphataseprotein kinase BProtein kinase Cmitogen-activated kinaseextracellular signal-regulated kinasesGlutathioneN-methyl-d-aspartate receptormu-opioid receptor
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Authors
Patricia I. Oteiza,