| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10738190 | Free Radical Biology and Medicine | 2012 | 11 Pages |
Abstract
⺠A redox-dependent regulation of Akt phosphorylation in PTEN null cells. ⺠Redox imbalance in PTEN null cells increases intracellular reducing capacity. ⺠Reduced cytosolic milieu in PTEN null cells prevents Akt Thr308 dephosphorylation. ⺠Decrease in superoxide favors dephosphorylation of cytosolic Akt by PP2A.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Ageing
Authors
Le Luo, Jaspal Kaur Kumar, Marie-Véronique Clément,