Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10738205 | Free Radical Biology and Medicine | 2012 | 9 Pages |
Abstract
⺠RNA oxidation is more abundant than DNA oxidation. ⺠High levels of oxidized RNA are found in degenerative brain diseases. ⺠General RNA oxidation is measured by 8-oxoGuo excretion into urine. ⺠General RNA oxidation predicts death in type 2 diabetes. ⺠RNA may be a novel and important mechanism of diseases such as diabetes, degenerative brain diseases, and hemochromatosis.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Ageing
Authors
Henrik E. Poulsen, Elisabeth Specht, Kasper Broedbaek, Trine Henriksen, Christina Ellervik, Thomas Mandrup-Poulsen, Morten Tonnesen, Peter E. Nielsen, Henrik U. Andersen, Allan Weimann,