Article ID Journal Published Year Pages File Type
10738209 Free Radical Biology and Medicine 2012 13 Pages PDF
Abstract
► MnTE-2-PyP5 + enhances dexamethasone-induced apoptosis in lymphoma. ► MnTE-2-PyP5 + acts as a pro-oxidant. ► MnTE-2-PyP5 + depletes glutathione and glutathionylates proteins. ► MnTE-2-PyP5 + glutathionylates and inhibits NF-κB to enhance apoptosis. ► Glutathione is essential for MnTE-2-PyP5 + activity.
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Preview
Manganese Porphyrin, MnTE-2-PyP5 +, Acts as a Pro-Oxidant to Potentiate Glucocorticoid-Induced Apoptosis in Lymphoma Cells
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