| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10738222 | Free Radical Biology and Medicine | 2012 | 9 Pages |
Abstract
⺠β-Caryophyllene (BCP) is a constituent of many essential oils of spice/food plants. ⺠Cisplatin (CIS) is a widely used anticancer drug that induces nephrotoxicity. ⺠CIS nephrotoxicity involves oxidative stress and the inflammatory response. ⺠BCP attenuates CIS-induced kidney inflammation, oxidative stress, and injury ⺠The protective effect of BCP is mediated via cannabinoid 2 receptors
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Authors
Béla Horváth, Partha Mukhopadhyay, Malek Kechrid, Vivek Patel, Galin Tanchian, David A. Wink, Jürg Gertsch, Pál Pacher,