Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10738228 | Free Radical Biology and Medicine | 2012 | 10 Pages |
Abstract
⺠Paraoxonase-1 (PON1) stimulates the capacity of HDL to mediate cholesterol efflux. ⺠PON1 upregulates ABCA1 gene and protein expression on J774 macrophages. ⺠PON1 stimulates the association of apo-AI with ABCA1 to stimulate cholesterol efflux. ⺠PON1 acts via an apo-AI-like mechanism to mediate cholesterol efflux.
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Authors
Hicham Berrougui, Soumaya Loued, Abdelouahed Khalil,