Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10738237 | Free Radical Biology and Medicine | 2012 | 12 Pages |
Abstract
⺠Carbonylation is a histone modification that occurs during cell proliferation. ⺠Histone carbonylation follows a pattern similar to that of cellular GSH levels. ⺠Histone carbonylation is involved in histone degradation by the nuclear proteasome. ⺠PARP activity is important for histone detoxification.
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Authors
José Luis GarcÃa-Giménez, Ana MarÃa Velázquez Ledesma, Isabel Esmoris, Carlos Romá-Mateo, Pascual Sanz, José Viña, Federico V. Pallardó,