Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10738276 | Free Radical Biology and Medicine | 2012 | 8 Pages |
Abstract
⺠OGG1 excising oxidized guanine in DNA harbors the Ser326Cys polymorphism. ⺠Cys/Cys carriers had elevated level of oxidized DNA bases in mononuclear blood cells. ⺠There was similar DNA repair activity in cells from subjects with different genotype. ⺠Expression of enzymes preventing oxidized guanine in DNA did not depend on Ser326Cys.
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Authors
Annie Jensen, Mille Løhr, Louise Eriksen, Morten Grønbæk, Elad Dorry, Steffen Loft, Peter Møller,