Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10738279 | Free Radical Biology and Medicine | 2012 | 9 Pages |
Abstract
⺠Low but not high glucose generated superoxide in the pancreatic beta cell line INS1. ⺠The effect of low glucose was rapid and reversible. ⺠Low glucose-induced superoxide production localized at complex 1. ⺠Low glucose also induced AMPK activation. ⺠AMPK activation was ROS-dependent and AMP, LKB1 and CaMKK independent.
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Authors
Alexandre Sarre, Jessica Gabrielli, Guillaume Vial, Xavier M. Leverve, Françoise Assimacopoulos-Jeannet,