Article ID Journal Published Year Pages File Type
10738289 Free Radical Biology and Medicine 2012 10 Pages PDF
Abstract
► Glutamate-induced neurotoxicity involves Ca2 +-dependent ROS production. ► Down-regulation of Homer 1b/c attenuates glutamate-induced neurotoxicity. ► Down-regulation of Homer1b/c inhibits glutamate-induced release of ER Ca2 +. ► Down-regulation of Homer1b/c reduces glutamate-induced ER stress. ► Down-regulation of Homer1b/c improves mitochondria function.
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