Article ID Journal Published Year Pages File Type
10738300 Free Radical Biology and Medicine 2011 11 Pages PDF
Abstract
► Doxorubicin is an antitumoral agent with high cardiotoxicity. ► Metformin is an antidiabetic drug which exerts cardioprotective effects. ► The metformin pretreatment protects cardiomyocytes from doxorubicin-induced damage. ► The cardiac adiponectin system plays an important role in this protective action.
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Authors
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