Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10738304 | Free Radical Biology and Medicine | 2011 | 10 Pages |
Abstract
⺠Chronic arsenic exposure causes cellular oxidative damage ⺠Quercetin a polyphenolic hydrophobic natural free radical scavenger ⺠hydrophilic compound DMSA is used in arsenic chelation therapy ⺠nanoencapsulation allows simultaneous delivery of these drugs in oral route ⺠it acted synergistically in management of arsenic accumulation & oxidative damage
Keywords
PLGANQCPolylactide-co-glycolide5-(and-6)-chloromethyl-2′,7′-dichlorodihydrofluorescein diacetate acetyl esterDMABCM-H2DCFDADCIPDPHDMSAGSHSDHAFM2,6-dichloroindophenolROSmeso-2,3-dimercaptosuccinic acidBrdUDiphenylhexatrienedidodecyldimethylammonium bromideFree radicalsBBBBlood–brain barriersuccinate dehydrogenaseMitochondriaAtomic Force MicroscopeNanocapsulesHematoxylin and Eosinreduced glutathioneQuercetinReactive oxygen species
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Authors
Swarupa Ghosh, Sandhya Rekha Dungdung, Somsubhra Thakur Chowdhury, Ardhendu K. Mandal, Sibani Sarkar, Debasree Ghosh, Nirmalendu Das,