| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10738307 | Free Radical Biology and Medicine | 2011 | 8 Pages |
Abstract
⺠Omeprazole treatment attenuates hyperoxia-induced ROS generation and inflammation. ⺠Omeprazole protects pulmonary cells against oxygen cytotoxicity. ⺠Omeprazole induces human CYP1A1 in H441 cells via the aryl hydrocarbon receptor. ⺠Aryl hydrocarbon receptor knockdown abrogates the beneficial effects of omeprazole.
Keywords
CM-H2DCF-DAAHR5-(and-6)-chloromethyl-2′,7′-dichlorodihydrofluorescein diacetateXTTARDSCyPHDAC1MCP-1BPDDMSOROSOxidant stressinflammationOmeprazoleBronchopulmonary dysplasiaDimethyl sulfoxideFree radicalsAcute respiratory distress syndromeCytochrome P450Monocyte chemotactic protein-1Reactive oxygen speciesaryl hydrocarbon receptor
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Authors
Binoy Shivanna, Chun Chu, Stephen E. Welty, Weiwu Jiang, Lihua Wang, Xanthi I. Couroucli, Bhagavatula Moorthy,