Article ID Journal Published Year Pages File Type
10738474 Free Radical Biology and Medicine 2011 11 Pages PDF
Abstract
► Hg2+ up-regulates human NQO1 primarily through a transcriptional mechanism. ► Hg2+ may have cytoprotective properties by increasing the expression of NQO1. ► Nrf2 is involved in the regulation of NQO1 by Hg2+. ► We demonstrated that the AhR level is dependent on the expression of Nrf2.
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