| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10738479 | Free Radical Biology and Medicine | 2011 | 10 Pages |
Abstract
⺠We investigate the role of HO-1 in development of squamous cell carcinoma in mice. ⺠HO-1 deficient mice are more vulnerable to the DMBA/PMA-induced skin injury. ⺠Lack of HO-1 results in the development of large, but benign papillomas. ⺠HO-1 expression facilitates transformation of growing tumors to malignant carcinoma. ⺠HO-1 expression promotes the c-myc mediated transformation of primary fibroblasts.
Keywords
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Authors
Halina Was, Malgorzata Sokolowska, Aleksandra Sierpniowska, PaweÅ Dominik, Klaudia Skrzypek, Bozena Lackowska, Antoni Pratnicki, Anna Grochot-Przeczek, Hevidar Taha, Jerzy Kotlinowski, Magdalena Kozakowska, Andrzej Mazan, Witold Nowak, Lucie Muchova,