Article ID Journal Published Year Pages File Type
10738483 Free Radical Biology and Medicine 2011 13 Pages PDF
Abstract
► In this study we examined the protective mechanism of ALDH2 after alcohol intake. ► ALDH2 was found to rescue alcohol-induced cardiac dysfunction and remodeling. ► The beneficial effect of ALDH2 was mediated through Akt and AMPK signaling. ► ALDH2 exerted its protection through regulation of autophagic flux.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Ageing
Authors
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