Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10738483 | Free Radical Biology and Medicine | 2011 | 13 Pages |
Abstract
⺠In this study we examined the protective mechanism of ALDH2 after alcohol intake. ⺠ALDH2 was found to rescue alcohol-induced cardiac dysfunction and remodeling. ⺠The beneficial effect of ALDH2 was mediated through Akt and AMPK signaling. ⺠ALDH2 exerted its protection through regulation of autophagic flux.
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Authors
Wei Ge, Rui Guo, Jun Ren,