| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10738491 | Free Radical Biology and Medicine | 2011 | 7 Pages |
Abstract
⺠Indomethacin exacerbates gastric damage in adjuvant arthritis rats. ⺠We evaluated new nitroxides as imaging agents and antioxidants. ⺠OMRI imaging using all tested nitroxides showed a redox imbalance in the stomach. ⺠Effects of nitroxides on lipid peroxide, IL-1β, and CINC/gro were different.
Keywords
NSAIDSOMRIFOVPGE2TBARSNSAIDROIESRCOXnuclear magnetic resonanceROSArthritisadjuvant arthritisRheumatoid arthritisAntioxidantscyclooxygenaseinterleukinDark AgoutiNMRMagnetic resonance imagingnonsteroidal anti-inflammatory drugFree radicalsElectron spin resonanceGastric ulcerSODTempolSuperoxide dismutasecytokine-induced neutrophil chemoattractantregion of interestthiobarbituric acid-reactive substancesField of viewNitroxideProstaglandin E2CINCReactive oxygen species
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Authors
Hisato Deguchi, Keiji Yasukawa, Toshihide Yamasaki, Fumiya Mito, Yuichi Kinoshita, Tatsuya Naganuma, Suguru Sato, Mayumi Yamato, Kazuhiro Ichikawa, Kiyoshi Sakai, Hideo Utsumi, Ken-ichi Yamada,