Article ID Journal Published Year Pages File Type
10743193 Maturitas 2015 5 Pages PDF
Abstract
Recent clinical data supports a role for T in BCA prevention. Women with symptoms of hormone deficiency treated with pharmacological doses of T alone or in combination with anastrozole (A), delivered by subcutaneous implants, had a reduced incidence of BCA. In addition, T combined with A effectively treated symptoms of hormone deficiency in BCA survivors and was not associated with recurrent disease. Most notably, T + A implants placed in breast tissue surrounding malignant tumors significantly reduced BCA tumor size, further supporting T direct antiproliferative, protective and therapeutic effect.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Ageing
Authors
, ,