Diabesity: Palliating, curing or preventing the dysmetabolic diathesis

This opinionated evidence-based selective review addresses flawed concepts related to “obesity”, bariatric surgery and approaches to treatment and prevention of a dysmetabolic syndrome of overnutrition and underactivity from the perspective of developmental origins of diseases prevalent in mid-life and beyond. Innovations focus on methods affecting appetite regulation and energy expenditure applicable throughout the life-cycle on the individual level but with transgenerational population-wide implications. Readers can expect new knowledge and enhanced understanding of a global health problem: “diabesity”.