Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10743572 | Maturitas | 2013 | 5 Pages |
Abstract
We could demonstrate a significant proliferative effect of MPA when combined with high concentrations of growth factors. This effect was more pronounced in breast cancer cells overexpressing PGRMC1. These results may be of clinical relevance since in the combined WHI trial an increased breast cancer risk was found during treatment with conjugated equine estrogens plus MPA.
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Authors
Jing Zhou, Qi Yu, Rong Chen, Harald Seeger, Tanja Fehm, Michael A. Cahill, Alfred O. Mueck, Hans Neubauer,