| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10745039 | Parkinsonism & Related Disorders | 2015 | 6 Pages |
Abstract
Pallidal microdialysis is a promising intraoperative monitoring tool to better understand pathophysiological implications in movement disorders and therapeutic mechanisms of high frequency stimulation. The increased inhibitory tone of GPi neurons and the subsequent thalamic inhibition could be one of the key mechanisms of GPi deep brain stimulation in dystonia. Such a mechanism may explain how competing (dystonic) movements can be suppressed in GPi/thalamic circuits in favour of desired motor programs.
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Authors
V.M. Tronnier, A. Domingo, C.K. Moll, D. Rasche, C. Mohr, R. Rosales, P. Capetian, R.D. Jamora, L.V. Lee, A. Münchau, C.C. Diesta, V. Tadic, C. Klein, N. Brüggemann, A. Moser,