| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10745121 | Parkinsonism & Related Disorders | 2015 | 6 Pages |
Abstract
Benefits on the off-medication symptoms of PD obtained acutely with GPe-DBS are in general not sustained. Similarly, the effects of GPi-DBS on the off medication symptoms of PD, can evolve over short periods of time presumably as a result of changes in network-wide neuronal plasticity. These clinical observations provide further insight into DBS mechanism of action, and can also help inform optimal methods of GPi-DBS programming.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Ageing
Authors
A. Angeli, H. Akram, A. Zacharia, P. Limousin, M. Hariz, L. Zrinzo, T. Foltynie,