Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10745232 | Parkinsonism & Related Disorders | 2014 | 30 Pages |
Abstract
Prefrontal cortex atrophy in PD has an additional effect to dopamine replacement therapy on the generation of NPS in these patients. These findings are an important step towards the delineation of atrophy vs. neurochemical imbalance in PD, and the results emphasize the importance of considering interactions between prefrontal atrophy and neurochemical dysfunction in the genesis of neuropsychiatric symptoms in PD.
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Authors
C. O'Callaghan, J.M. Shine, S.J.G. Lewis, M. Hornberger,