| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10745576 | Parkinsonism & Related Disorders | 2014 | 6 Pages |
Abstract
The rs921451 and rs3837091 polymorphisms of the DDC gene promoter influence the motor response to l-dopa but do not significantly change peripheral pharmacokinetic parameters for l-dopa and dopamine. Our results suggest that DDC may be a genetic modifier of the l-dopa response in Parkinson's disease.
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Authors
David Devos, Stéphanie Lejeune, Florence Cormier-Dequaire, Khadija Tahiri, Fanny Charbonnier-Beaupel, Nathalie Rouaix, Alain Duhamel, Bernard Sablonnière, Anne-Marie Bonnet, Cecilia Bonnet, Noel Zahr, Jean Costentin, Marie Vidailhet,