Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10745815 | Parkinsonism & Related Disorders | 2013 | 6 Pages |
Abstract
Simvastatin reduced dyskinesia in primates using high doses over 3Â mg/kg but the exploratory trial in patients revealed no effect at 40Â mg/d suggesting that higher doses, not compatible with a safe prolonged administration, are necessary.
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Authors
François Tison, Laurence Nègre-Pagès, Wassilios G. Meissner, Sandrine Dupouy, Qin Li, Marie-Laure Thiolat, Thibaud Thiollier, Monique Galitzky, Fabienne Ory-Magne, Agathe Milhet, Laurent Marquine, Umberto Spampinato, Olivier Rascol, Erwan Bezard,