Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10745972 | Parkinsonism & Related Disorders | 2013 | 7 Pages |
Abstract
Safinamide and amantadine reduced LID in this primate model while only safinamide increased the duration of the antiparkinsonian response of l-DOPA, suggesting that safinamide may have effects on LID that are pharmacologically distinct from amantadine, which is in current clinical use for control of LID.
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Authors
Laurent Grégoire, Vincent A. Jourdain, Matthew Townsend, Arthur Roach, Thérèse Di Paolo,