Article ID Journal Published Year Pages File Type
10879977 Toxicon 2012 7 Pages PDF
Abstract
► Mouse CMAP assay could determine the potency of botulinum neurotoxin type A. ► This prevalidation experiment was based on ICH guideline. ► Mouse CMAP assay was shown to be a suitable alternative to the LD50 potency test. ► Mouse CMAP assay also satisfies the Three Rs requirement.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry, Genetics and Molecular Biology (General)
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