Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10879977 | Toxicon | 2012 | 7 Pages |
Abstract
⺠Mouse CMAP assay could determine the potency of botulinum neurotoxin type A. ⺠This prevalidation experiment was based on ICH guideline. âºÂ Mouse CMAP assay was shown to be a suitable alternative to the LD50 potency test. âºÂ Mouse CMAP assay also satisfies the Three Rs requirement.
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Biochemistry, Genetics and Molecular Biology (General)
Authors
Soo-Hyun Kim, Sung-Beom Kim, Gi-Hyeok Yang, Chang-Hoon Rhee,