Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10879979 | Toxicon | 2012 | 9 Pages |
Abstract
⺠Zearalenone decreases glutathione-S-transferase activity in the mice kidney and testes. ⺠Oxidative stress enzymatic markers are related to acute zearalenone toxicity in kidney, liver and testes of Swiss albino mice. ⺠Zearalenone elicits oligozoospermia in mice, as determined by the reduced number and motility of spermatozoa. âºÂ Zearalenone alters haematological and reproductive parameters in Swiss albino male mice.
Keywords
β-zearalenolERαERβGSTM1CDNBα-Zearalanolα-ZOLDTNBα-ZearalenolTBARSβ-zearalanolβ-ZOLERSLD50GSHTCATBAGSTCATNPSHZEAMDAGSTM35,5′-dithiobis (2-nitrobenzoic acid)ROSspermatozoatrichloroacetic acidThiobarbituric acidTestesOxidative stresslethal doseZearalenoneSODSuperoxide dismutasemalondialdehydethiobarbituric acid reactive substancesMycotoxinCatalasereduced glutathioneLiverKidneyglutathione S-transferaseglutathione S-transferase M1Reactive oxygen species
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Authors
Silvana Peterini Boeira, Carlos Borges Filho, Lucian Del'Fabbro, Luiz Fernando Freire Royes, Cristiano Ricardo Jessé, Mauro Schneider Oliveira, Ana Flávia Furian,