| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10879984 | Toxicon | 2012 | 10 Pages |
Abstract
⺠We examined the mechanism of endothelial cell cytotoxicity induced by Loxosceles intermedia. ⺠Brown spider venom leads to important changes in cellular adhesion. ⺠The loss of cell anchorage provides the signal to initiate apoptosis. ⺠Venom triggers endothelial cell death by an apoptotic mechanism known as anoikis.
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Authors
Jenifer Nowatzki, Reginaldo Vieira Sene, Katia Sabrina Paludo, Luiz Eduardo Rizzo, Fernando Souza-Fonseca-Guimarães, Silvio Sanches Veiga, Helena Bonciani Nader, Célia Regina C. Franco, Edvaldo S. Trindade,