| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10880002 | Toxicon | 2012 | 12 Pages |
Abstract
⺠Mass spectrometry provided expressional correlation within Conus venom extracts. ⺠Amino acid analysis allowed for the quantification of venom production. ⺠Milked venom demonstrates expressional variability. ⺠Toxinological understanding of cone shell milked venom enhances drug-discovery.
Keywords
PTMConopeptidesnAChRDHBIC50ESI-MSMECNPDACIDRP-HPLC/UV2,5-dihydroxybenzoic acidLC/MSm/ztris(2-carboxyethyl)phosphineAqueousphoto diode arrayAcetonitrileElectrospray Ionization Mass Spectrometrypost-translational modificationAmino acid analysiscollision induced dissociationTotal VolumeCone snailaq.DaltonsRetention timeTCEPToxinsMass spectrometrySEMPeptide quantificationmass to charge ratioNavthe half maximal inhibitory concentrationEnvenomationConotoxinsnicotinic acetylcholine receptor
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Authors
Joycelyn B.S. Chun, Margaret R. Baker, Do H. Kim, Majdouline LeRoy, Priamo Toribo, Jon-Paul Bingham,