| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10880016 | Toxicon | 2011 | 8 Pages |
Abstract
⺠Phα1β induced longer postoperative pain reduction effect than Ï-conotoxin MVIIA or morphine. ⺠The drugs did not change mean arterial pressure after intrathechal injection. ⺠Intrathecal administration of Ï-conotoxin MVIIA increased the heart rate while Phα1β or morphine had no effect. ⺠The drugs did not alter neurological performance and the expression of pro or anti-inflammatory cytokines. ⺠Phα1β has a potential application in the management of postoperative pain with low side effects.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry, Genetics and Molecular Biology (General)
Authors
A.H. de Souza, M.C. Lima, C.C. Drewes, J.F. da Silva, K.C.L. Torres, E.M.R. Pereira, C.J. Junior, L.B. Vieira, M.N. Cordeiro, M. Richardson, R.S. Gomez, M.A. Romano-Silva, J. Ferreira, M.V. Gomez,