Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10880054 | Toxicon | 2011 | 11 Pages |
Abstract
⺠The majority of Micrurus venom components are neurotoxins and phospholipase A2s, this study demonstrated that these venoms also contain high-molecular-weight proteins between 50 and 150 kDa that target the hemostatic system. ⺠The Micrurus venoms contained fibrino(geno)lytic activity, they inhibited platelet aggregation, as well as factor Xa and/or plasmin-like activities. ⺠This is the first report on thrombin-like and fibrino(geno)lytic activity and plasmin or factor Xa inhibitors described in Micrurus venoms.
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Authors
Ana M. Salazar, Jeilyn Vivas, Elda E. Sánchez, Alexis RodrÃguez-Acosta, Carlos Ibarra, Amparo Gil, Zoila Carvajal, MarÃa E. Girón, Amalid Estrella, Luis F. Navarrete, Belsy Guerrero,