Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10880075 | Toxicon | 2012 | 7 Pages |
Abstract
⺠JZTX-XIII acts as gating modifier of voltage-gated K+ channels. ⺠JZTX-XIII potently inhibits Kv2.1 and Kv4.1 channels. ⺠JZTX-XIII shows no Nav1.5 channel activity. ⺠Residues of Glu10 and Glu17 in JZTX-XIII might impair the binding to Nav1.5 channel.
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Authors
Chunhua Yuan, Zhonghua Liu, Weijun Hu, Tianming Gao, Songping Liang,