Article ID Journal Published Year Pages File Type
10880075 Toxicon 2012 7 Pages PDF
Abstract
► JZTX-XIII acts as gating modifier of voltage-gated K+ channels. ► JZTX-XIII potently inhibits Kv2.1 and Kv4.1 channels. ► JZTX-XIII shows no Nav1.5 channel activity. ► Residues of Glu10 and Glu17 in JZTX-XIII might impair the binding to Nav1.5 channel.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry, Genetics and Molecular Biology (General)
Authors
, , , , ,