| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10880076 | Toxicon | 2012 | 11 Pages |
Abstract
⺠This is the first report on human ScFv that neutralizes TTX ion channel activity. ⺠The human ScFv rescued TTX intoxicated mice from lethality. ⺠Molecular mechanisms of the human ScFv in TTX neutralization were revealed. ⺠The human ScFv warrants developing further as anti-TTX remedy.
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Authors
Monrat Chulanetra, Kunan Bangphoomi, Nitat Sookrung, Jeeraphong Thanongsaksrikul, Potjanee Srimanote, Yuwaporn Sakolvarvaree, Kiattawee Choowongkomon, Wanpen Chaicumpa,