Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10880123 | Toxicon | 2011 | 11 Pages |
Abstract
BoNT A toxin complexes have evolved to quickly respond to specific environmental changes by efficient release of the neurotoxin. During pharmaceutical production and reconstitution of BoNT A products, the same principles effect the quantitative dissociation of 900Â kDa complexes and release of free neurotoxin prior to injection into target tissues.
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Authors
Karl-Heinz Eisele, Klaus Fink, Martin Vey, Harold V. Taylor,