Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10880130 | Toxicon | 2011 | 6 Pages |
Abstract
Both pre- and post-column oxidation liquid chromatography methods with fluorescence detection are available for detecting paralytic shellfish toxins. Each method has been evaluated in multiple laboratories and validated as a potential alternative to the mouse bioassay. This communication compares the advantages and limitations of both methods. For a given laboratory, the selection of either method may be based primarily on practicality and less on any deficiencies in scientific merit.
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Authors
Stacey L. DeGrasse, Jeffrey van de Riet, Robert Hatfield, Andrew Turner,