Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10880156 | Toxicon | 2011 | 4 Pages |
Abstract
Phospholipase A2 inhibitors (PLIs) are glycoproteins secreted by snake liver into the circulating blood aiming the self-protection against toxic venom phospholipases A2. In the present study, we describe the first complete nucleotide sequence of a βPLI from venom glands of a New World snake, Lachesis muta. The deduced primary structure was compared to other known βPLIs and recent literature findings of other possible roles of PLIs in snakes are discussed.
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Authors
Rebeca Mascarenhas Lima, Maria Inácia Estevão-Costa, Inácio L.M. Junqueira-de-Azevedo, Paulo Lee Ho, Marcelo Ribeiro Vasconcelos Diniz, Consuelo Latorre Fortes-Dias,