Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10880353 | Toxicon | 2005 | 5 Pages |
Abstract
Linear free polyamines were characterized in the venom of the spiders Agelenopsis aperta, Hololena curta, and Paracoelotes birulai by RP-HPLC coupled to mass spectrometry. The several linear polyamines found were tetramine, pentamine, and hexamine derivatives. Some of these natural products were identified as N-hydroxylated, guanidylated, or acetylated compounds. In addition, the biosynthetical pathway leading to the formation of acylpolyamines in spider venoms is discussed.
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Authors
Manuel Tzouros, Sergiy Chesnov, Stefan Bienz, Manfred Hesse, Laurent Bigler,