Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10880391 | Toxicon | 2011 | 9 Pages |
Abstract
⺠A novel formulation of botulinum neurotoxin is described. ⺠Muscle force generation and voluntary running distance in mice are used. ⺠Novel formulation RT002 exhibits reduced diffusion allowing for higher dose. ⺠RT002 exhibits increased duration of action and reduced systemic toxicity.
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Authors
Hongran F. Stone, Zhao Zhu, Thai Q.D. Thach, Curtis L. Ruegg,