Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10880672 | Toxicon | 2005 | 15 Pages |
Abstract
We show that the hydrae express orthologs of cnidarian phospholipase A2 toxins and cytolysins belonging to the actinoporin family, but could not find orthologs of the 'classic' short chain neurotoxins affecting sodium and potassium conductance. Hydrae also express proteins similar to elapid-like phospholipases, CRISP proteins, Prokineticin-like polypeptides and toxic deoxyribonucleases. Our results illustrate a high level of complexity in the hydra allomonal system, suggest that several toxins represent a basal component of all cnidarian allomones, and raise the intriguing possibility that similar proteins may fulfill both endogenous and allomonal roles in cnidaria.
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Authors
Daniel Sher, Alin Knebel, Tamar Bsor, Nir Nesher, Tzachy Tal, David Morgenstern, Eran Cohen, Yelena Fishman, Eliahu Zlotkin,