| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10882940 | Mitochondrion | 2012 | 10 Pages |
Abstract
⺠When electron transport produces cell injury, proximal blockade can protect. ⺠Approaches to target complexes I and II promote cytoprotection. ⺠Mitochondria-localized STAT3 directly regulates electron transport. ⺠Therapeutic approaches include reversible inhibitors of complex I. ⺠Other treatment options include the modulation of endogenous signaling pathways.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biophysics
Authors
Karol Szczepanek, Qun Chen, Andrew C. Larner, Edward J. Lesnefsky,