| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10882942 | Mitochondrion | 2012 | 11 Pages |
Abstract
⺠Glaucoma is the leading cause of irreversible blindness worldwide. ⺠Complex genetic influences may lead to mitochondrial dysfunction in glaucoma. ⺠A variety of genes involved in mitochondrial function and structure are presented.
Keywords
TNFaNTGTP53POAGMFNSOD2CYP1B1iOpRGCPARLLHONOXPHOSGSTHTGNOS3Tumour protein p53HRTADOAMitochondrial DNANuclear DNAROSoptic atrophy 1autosomal dominant optic atrophytumour necrosis factor alphamtDNAretinal ganglion cellSuperoxide dismutase 2Oxidative phosphorylationIntraocular pressureMitofusinMitochondriaLeber's hereditary optic neuropathyNitric oxide synthase 3Single nucleotide polymorphismSNPGeneticsglutathione S-transferasenormal tension glaucomaprimary open angle glaucomaReactive oxygen species
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Authors
Gerassimos Lascaratos, David F. Garway-Heath, Colin E. Willoughby, Kai-Yin Chau, Anthony H.V. Schapira,