Article ID Journal Published Year Pages File Type
10882957 Mitochondrion 2012 8 Pages PDF
Abstract
► Mfn1 level in bovine cloned embryo can be altered by transgenic or RNAi technology. ► Upregulation of Mfn1 will increase the development rate of bovine cloned embryo. ► Overexpression of Mfn1 in bovine cloned embryo will restrain the fragmentation. ► Overexpression of Mfn1will enhance ATP generation and increase Δψm. ► Upregulation of Mfn1 will decrease H2O2 concentration in bovine cloned embryos.
Keywords
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biophysics
Preview
High expression of Mfn1 promotes early development of bovine SCNT embryos: Improvement of mitochondrial membrane potential and oxidative metabolism
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