Article ID Journal Published Year Pages File Type
10882959 Mitochondrion 2012 9 Pages PDF
Abstract
► LPS induces the activation of nNOS in oligodendrocytes. ► nNOS activation leads to mitochondrial injury and the release of cytochrome c. ► Mitochondrial injury is reversed by nNOS specific inhibitors. ► Inhibitors of NOS activity are potential agents to reverse oligodendrocyte injury.
Keywords
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biophysics
Preview
nNOS mediated mitochondrial injury in LPS stimulated oligodendrocytes
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