Article ID Journal Published Year Pages File Type
10883093 Mitochondrion 2011 5 Pages PDF
Abstract
► We studied the rescuing of human equivalent yeast mutants in mttRNALeu, Val and Ile. ► Thecarboxy-terminal of human and yeast mtleuRShas full suppressing activity. ► The overexpressed human C-terminal domain isfound to be localizedin mitochondria. ► Smaller peptides from C-terminal maintain rescuing capability. ► Suppression of defective phenotypes could be due to an RNA stabilizing capability.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biophysics
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