Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10883093 | Mitochondrion | 2011 | 5 Pages |
Abstract
⺠We studied the rescuing of human equivalent yeast mutants in mttRNALeu, Val and Ile. ⺠Thecarboxy-terminal of human and yeast mtleuRShas full suppressing activity. ⺠The overexpressed human C-terminal domain isfound to be localizedin mitochondria. ⺠Smaller peptides from C-terminal maintain rescuing capability. ⺠Suppression of defective phenotypes could be due to an RNA stabilizing capability.
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Authors
Silvia Francisci, Arianna Montanari, Cristina De Luca, Laura Frontali,