| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10885979 | Drug Discovery Today | 2014 | 7 Pages |
Abstract
- Twenty-four libraries generated using natural products as guiding structures were analyzed.
- The variation of two main lead-like descriptors (MW, logP) within the libraries was analyzed.
- Three distributions trends (MW vs logP) in the library generation were identified.
- A schematic approach for the design of a lead-like library is suggested.
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Authors
Mauro Pascolutti, Ronald J. Quinn,