Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10886025 | Drug Discovery Today | 2015 | 11 Pages |
Abstract
- Microbial amphiphiles have emerged as new-generation anticancer molecules.
- These molecules modulate apoptosis, cell cycle arrest and angiogenesis.
- These molecules inhibit crucial signaling pathways such as Akt, ERK/JNK and JAK/STAT.
- Hydrophobic and hydrophilic moieties interact with cancer cell membrane components.
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Authors
Goutam Dey, Rashmi Bharti, Ramkrishna Sen, Mahitosh Mandal,