Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10886131 | Drug Discovery Today | 2014 | 5 Pages |
Abstract
The tissue factor-coagulation factor VIIa complex (TF-fVIIa) is a well-validated biological target and has been the focus of extensive research directed toward the discovery of novel oral antithrombotics. This review briefly summarizes the key antithrombotic target validation data and provides an update on recent advances in small molecule TF-fVIIa inhibitors.
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Authors
E. Scott Priestley,