Article ID Journal Published Year Pages File Type
10886131 Drug Discovery Today 2014 5 Pages PDF
Abstract
The tissue factor-coagulation factor VIIa complex (TF-fVIIa) is a well-validated biological target and has been the focus of extensive research directed toward the discovery of novel oral antithrombotics. This review briefly summarizes the key antithrombotic target validation data and provides an update on recent advances in small molecule TF-fVIIa inhibitors.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biotechnology
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